P10R (p.Pro10Arg) variant of GRIN2D (O15399)
P10R (p.Pro10Arg) in GRIN2D (O15399) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
P10R (p.Pro10Arg) variant details
- p.Pro10Arg
- gnomAD 19-48398421-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.10
- ESM-1b 0.00
- AlphaMissense 0.10
- CADD 25.20
- PolyPhen-2 0.73
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available