L20P (p.Leu20Pro) variant of GRIN2D (O15399)
L20P (p.Leu20Pro) in GRIN2D (O15399) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
L20P (p.Leu20Pro) variant details
- p.Leu20Pro
- gnomAD 19-48398451-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- REVEL 0.21
- ESM-1b 0.51
- AlphaMissense 0.85
- CADD 26.20
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available