A21V (p.Ala21Val) variant of GRIN2D (O15399)
A21V (p.Ala21Val) in GRIN2D (O15399) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A21V (p.Ala21Val) variant details
- p.Ala21Val
- gnomAD rs1293786564
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.47
- CADD 21.20
- PolyPhen-2 0.17
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available