A21T (p.Ala21Thr) variant of GRIN2D (O15399)
A21T (p.Ala21Thr) in GRIN2D (O15399) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- gnomAD 19-48398453-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.62
- CADD 25.30
- PolyPhen-2 0.51
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available