R1463T (p.Arg1463Thr) variant of GRIN2B (Q13224)

Name: GRIN2B R1463T (p.Arg1463Thr) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-09-07
License: https://catvariant.com/terms-of-use

R1463T (p.Arg1463Thr) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.

R1463T (p.Arg1463Thr) variant details

p.Arg1463Thr
rs1408420096
gnomAD 12-13562850-C-G
Missense
Variant Prioritization Score for Impact Estimate 0.586
MetaLR 0.11
MetaSVM -0.98
CADD 22.70
PolyPhen-2 0.20
SIFT 0.01
Population evidence available
Structural context available
Literature evidence available