Q1451K (p.Gln1451Lys) variant of GRIN2B (Q13224)
Q1451K (p.Gln1451Lys) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
Q1451K (p.Gln1451Lys) variant details
- p.Gln1451Lys
- rs745597964
- gnomAD 12-13562887-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- MetaLR 0.02
- MetaSVM -0.98
- CADD 22.70
- PolyPhen-2 0.01
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available