P1462S (p.Pro1462Ser) variant of GRIN2B (Q13224)
P1462S (p.Pro1462Ser) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
P1462S (p.Pro1462Ser) variant details
- p.Pro1462Ser
- rs780659331
- gnomAD 12-13562854-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- MetaLR 0.06
- MetaSVM -1.12
- CADD 22.90
- PolyPhen-2 0.42
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available