P1457S (p.Pro1457Ser) variant of GRIN2B (Q13224)
P1457S (p.Pro1457Ser) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
P1457S (p.Pro1457Ser) variant details
- p.Pro1457Ser
- rs1317229312
- gnomAD 12-13562869-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- MetaLR 0.01
- MetaSVM -0.95
- CADD 21.80
- PolyPhen-2 0.01
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available