P1457R (p.Pro1457Arg) variant of GRIN2B (Q13224)
P1457R (p.Pro1457Arg) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
P1457R (p.Pro1457Arg) variant details
- p.Pro1457Arg
- gnomAD 12-13562868-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- MetaLR 0.02
- MetaSVM -1.06
- CADD 24.00
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available