P1454S (p.Pro1454Ser) variant of GRIN2B (Q13224)
P1454S (p.Pro1454Ser) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
P1454S (p.Pro1454Ser) variant details
- p.Pro1454Ser
- rs1948565765
- gnomAD 12-13562878-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- MetaLR 0.04
- MetaSVM -1.13
- CADD 23.80
- PolyPhen-2 0.74
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available