P1454A (p.Pro1454Ala) variant of GRIN2B (Q13224)
P1454A (p.Pro1454Ala) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
P1454A (p.Pro1454Ala) variant details
- p.Pro1454Ala
- gnomAD 12-13562878-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.57
- MetaLR 0.03
- MetaSVM -1.07
- CADD 23.00
- PolyPhen-2 0.09
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available