N1459D (p.Asn1459Asp) variant of GRIN2B (Q13224)
N1459D (p.Asn1459Asp) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
N1459D (p.Asn1459Asp) variant details
- p.Asn1459Asp
- rs1384338205
- gnomAD 12-13562863-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- MetaLR 0.03
- MetaSVM -1.07
- CADD 22.90
- PolyPhen-2 0.29
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available