N1453K (p.Asn1453Lys) variant of GRIN2B (Q13224)
N1453K (p.Asn1453Lys) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
N1453K (p.Asn1453Lys) variant details
- p.Asn1453Lys
- rs887589398
- gnomAD 12-13562879-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- MetaLR 0.02
- MetaSVM -0.99
- CADD 19.10
- PolyPhen-2 0.29
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available