N1453D (p.Asn1453Asp) variant of GRIN2B (Q13224)
N1453D (p.Asn1453Asp) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
N1453D (p.Asn1453Asp) variant details
- p.Asn1453Asp
- rs746663430
- gnomAD 12-13562881-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- MetaLR 0.03
- MetaSVM -1.01
- CADD 21.50
- PolyPhen-2 0.36
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available