L1434I (p.Leu1434Ile) variant of GRIN2B (Q13224)
L1434I (p.Leu1434Ile) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and published literature.
L1434I (p.Leu1434Ile) variant details
- p.Leu1434Ile
- rs1002108827
- gnomAD 12-13562938-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.559
- MetaLR 0.02
- MetaSVM -0.93
- CADD 21.70
- PolyPhen-2 0.12
- SIFT 0.09
- Population evidence available
- Literature evidence available