K1460R (p.Lys1460Arg) variant of GRIN2B (Q13224)
K1460R (p.Lys1460Arg) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
K1460R (p.Lys1460Arg) variant details
- p.Lys1460Arg
- rs757954618
- gnomAD 12-13562859-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- MetaLR 0.02
- MetaSVM -0.96
- CADD 20.50
- PolyPhen-2 0.29
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available