I1446T (p.Ile1446Thr) variant of GRIN2B (Q13224)
I1446T (p.Ile1446Thr) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and published literature.
I1446T (p.Ile1446Thr) variant details
- p.Ile1446Thr
- rs1301106301
- gnomAD 12-13562901-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.475
- MetaLR 0.02
- MetaSVM -0.99
- CADD 23.90
- PolyPhen-2 0.03
- SIFT 0.00
- Population evidence available
- Literature evidence available