C1455Y (p.Cys1455Tyr) variant of GRIN2B (Q13224)
C1455Y (p.Cys1455Tyr) in GRIN2B (Q13224) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
C1455Y (p.Cys1455Tyr) variant details
- p.Cys1455Tyr
- gnomAD 12-13562874-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- MetaLR 0.01
- MetaSVM -0.92
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available