G20V (p.Gly20Val) variant of GRIN2A (Q12879)
G20V (p.Gly20Val) in GRIN2A (Q12879) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
G20V (p.Gly20Val) variant details
- p.Gly20Val
- cosmic curated COSV58055
- TOPMed rs2050242121
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.07
- CADD 21.10
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available