A25G (p.Ala25Gly) variant of GRIN2A (Q12879)
A25G (p.Ala25Gly) in GRIN2A (Q12879) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A25G (p.Ala25Gly) variant details
- p.Ala25Gly
- 1000Genomes rs542256226
- ExAC rs542256226
- gnomAD rs542256226
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.04
- CADD 22.10
- PolyPhen-2 0.02
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available