S77L (p.Ser77Leu) variant of GRIN1 (Q05586)
S77L (p.Ser77Leu) in GRIN1 (Q05586) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
S77L (p.Ser77Leu) variant details
- p.Ser77Leu
- rs2131187092
- gnomAD 9-137139716-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.524
- REVEL 0.50
- CADD 23.70
- PolyPhen-2 0.81
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available