L60F (p.Leu60Phe) variant of GRIN1 (Q05586)
L60F (p.Leu60Phe) in GRIN1 (Q05586) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L60F (p.Leu60Phe) variant details
- p.Leu60Phe
- gnomAD 9-137139664-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.21
- CADD 20.10
- PolyPhen-2 0.06
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available