A21S (p.Ala21Ser) variant of GRIN1 (Q05586)
A21S (p.Ala21Ser) in GRIN1 (Q05586) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 9-137139547-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.05
- CADD 14.20
- PolyPhen-2 0.07
- SIFT 0.31
- Population evidence available
- Structural context available
- Literature evidence available