S12Y (p.Ser12Tyr) variant of GRIA2 (Glutamate receptor 2)
S12Y (p.Ser12Tyr) in GRIA2 (Glutamate receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
S12Y (p.Ser12Tyr) variant details
- p.Ser12Tyr
- gnomAD 4-157221077-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.20
- CADD 17.30
- PolyPhen-2 0.00
- SIFT 0.90
- Population evidence available
- Structural context available
- Literature evidence available