I4T (p.Ile4Thr) variant of GRIA2 (Glutamate receptor 2)
I4T (p.Ile4Thr) in GRIA2 (Glutamate receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
I4T (p.Ile4Thr) variant details
- p.Ile4Thr
- gnomAD 4-157221053-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.14
- CADD 23.10
- PolyPhen-2 0.05
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available