S65R (p.Ser65Arg) variant of GRIA1 (Glutamate receptor 1)
S65R (p.Ser65Arg) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S65R (p.Ser65Arg) variant details
- p.Ser65Arg
- ExAC rs778014621
- TOPMed rs778014621
- gnomAD rs778014621
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.46
- MetaLR 0.37
- MetaSVM -0.51
- CADD 5.43
- SIFT 0.18
- Most common in the HGDP:BIAKA population (allele frequency 0.18)
- Structural context available