Q37R (p.Gln37Arg) variant of GRIA1 (Glutamate receptor 1)
Q37R (p.Gln37Arg) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
Q37R (p.Gln37Arg) variant details
- p.Gln37Arg
- gnomAD 5-153493955-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.26
- MetaLR 0.07
- MetaSVM -1.11
- CADD 23.60
- PolyPhen-2 0.58
- SIFT 0.04
- Most common in the HGDP:MBUTI population (allele frequency 0.29)
- Structural context available
- Literature evidence available