N33Y (p.Asn33Tyr) variant of GRIA1 (Glutamate receptor 1)
N33Y (p.Asn33Tyr) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
N33Y (p.Asn33Tyr) variant details
- p.Asn33Tyr
- TOPMed rs1421139721
- gnomAD rs1421139721
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.25
- MetaLR 0.06
- MetaSVM -1.02
- CADD 23.80
- PolyPhen-2 0.11
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 0.00046)
- Structural context available