G29A (p.Gly29Ala) variant of GRIA1 (Glutamate receptor 1)
G29A (p.Gly29Ala) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G29A (p.Gly29Ala) variant details
- p.Gly29Ala
- cosmic curated COSV53620
- TOPMed rs1754169954
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.26
- MetaLR 0.39
- MetaSVM -0.31
- CADD 23.70
- PolyPhen-2 0.83
- SIFT 1.00
- Most common in the HGDP:KARITIANA population (allele frequency 0.35)
- Structural context available