G28R (p.Gly28Arg) variant of GRIA1 (Glutamate receptor 1)
G28R (p.Gly28Arg) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
G28R (p.Gly28Arg) variant details
- p.Gly28Arg
- gnomAD 5-153490970-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.62
- MetaLR 0.21
- MetaSVM -0.72
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.23
- Most common in the HGDP:KARITIANA population (allele frequency 0.35)
- Structural context available
- Literature evidence available