G18S (p.Gly18Ser) variant of GRIA1 (Glutamate receptor 1)
G18S (p.Gly18Ser) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G18S (p.Gly18Ser) variant details
- p.Gly18Ser
- gnomAD rs1411545506
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.18
- MetaLR 0.07
- MetaSVM -1.13
- CADD 20.30
- PolyPhen-2 0.14
- SIFT 0.15
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available