G18R (p.Gly18Arg) variant of GRIA1 (Glutamate receptor 1)
G18R (p.Gly18Arg) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
G18R (p.Gly18Arg) variant details
- p.Gly18Arg
- gnomAD 5-153490940-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.28
- MetaLR 0.08
- MetaSVM -1.10
- CADD 19.90
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the HGDP:SARDINIAN population (allele frequency 0.037)
- Structural context available
- Literature evidence available