G11S (p.Gly11Ser) variant of GRIA1 (Glutamate receptor 1)
G11S (p.Gly11Ser) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G11S (p.Gly11Ser) variant details
- p.Gly11Ser
- TOPMed rs1418777145
- gnomAD rs1418777145
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.10
- MetaLR 0.02
- MetaSVM -1.00
- CADD 20.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the HGDP:BASQUE population (allele frequency 0.023)
- Structural context available