F7S (p.Phe7Ser) variant of GRIA1 (Glutamate receptor 1)
F7S (p.Phe7Ser) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
F7S (p.Phe7Ser) variant details
- p.Phe7Ser
- gnomAD rs1232613217
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.15
- MetaLR 0.03
- MetaSVM -1.06
- CADD 21.70
- PolyPhen-2 0.03
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 0.00098)
- Structural context available