F5Y (p.Phe5Tyr) variant of GRIA1 (Glutamate receptor 1)
F5Y (p.Phe5Tyr) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
F5Y (p.Phe5Tyr) variant details
- p.Phe5Tyr
- gnomAD 5-153490902-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.16
- MetaLR 0.03
- MetaSVM -1.09
- CADD 21.70
- PolyPhen-2 0.16
- SIFT 0.10
- Most common in the HGDP:RUSSIAN population (allele frequency 0.02)
- Structural context available
- Literature evidence available