A15T (p.Ala15Thr) variant of GRIA1 (Glutamate receptor 1)
A15T (p.Ala15Thr) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A15T (p.Ala15Thr) variant details
- p.Ala15Thr
- TOPMed rs921859652
- gnomAD rs921859652
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.03
- MetaLR 0.02
- MetaSVM -0.99
- CADD 19.50
- PolyPhen-2 0.02
- SIFT 0.46
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available