A15S (p.Ala15Ser) variant of GRIA1 (Glutamate receptor 1)
A15S (p.Ala15Ser) in GRIA1 (Glutamate receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A15S (p.Ala15Ser) variant details
- p.Ala15Ser
- gnomAD 5-153490931-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.04
- MetaLR 0.02
- MetaSVM -0.98
- CADD 19.10
- PolyPhen-2 0.06
- SIFT 0.50
- Most common in the HGDP:SAN population (allele frequency 0.17)
- Structural context available
- Literature evidence available