Y37F (p.Tyr37Phe) variant of GNAS (P63092)
Y37F (p.Tyr37Phe) in GNAS (P63092) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
Y37F (p.Tyr37Phe) variant details
- p.Tyr37Phe
- ExAC rs777619747
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.29
- CADD 19.10
- PolyPhen-2 0.04
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available