C10Y (p.Cys10Tyr) variant of GNAQ (P50148)
C10Y (p.Cys10Tyr) in GNAQ (P50148) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
C10Y (p.Cys10Tyr) variant details
- p.Cys10Tyr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.762
- REVEL 0.76
- MetaLR 0.80
- MetaSVM 0.76
- CADD 25.20
- PolyPhen-2 0.97
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available