R21L (p.Arg21Leu) variant of GNAI1 (P63096)
R21L (p.Arg21Leu) in GNAI1 (P63096) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
R21L (p.Arg21Leu) variant details
- p.Arg21Leu
- gnomAD 7-80135222-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.666
- MetaLR 0.64
- MetaSVM 0.30
- CADD 24.90
- PolyPhen-2 0.16
- SIFT 0.44
- Population evidence available
- Structural context available
- Literature evidence available