L39F (p.Leu39Phe) variant of GNAI1 (P63096)
L39F (p.Leu39Phe) in GNAI1 (P63096) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
L39F (p.Leu39Phe) variant details
- p.Leu39Phe
- gnomAD 7-80135275-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.686
- MetaLR 0.91
- MetaSVM 1.01
- CADD 27.20
- PolyPhen-2 0.97
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available