G40S (p.Gly40Ser) variant of GNAI1 (P63096)
G40S (p.Gly40Ser) in GNAI1 (P63096) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact in the context of in NEDHISB. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
G40S (p.Gly40Ser) variant details
- p.Gly40Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- in NEDHISB
- Missense
- Variant Prioritization Score for Impact Estimate 0.795
- CADD 35.00
- PolyPhen-2 0.87
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact. (in NEDHISB)
- Population evidence available
- Structural context available