E33K (p.Glu33Lys) variant of GNAI1 (P63096)
E33K (p.Glu33Lys) in GNAI1 (P63096) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
E33K (p.Glu33Lys) variant details
- p.Glu33Lys
- NCI-TCGA TCGA novel
- Ensembl rs1583996658
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.698
- CADD 24.40
- PolyPhen-2 0.45
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available