R31W (p.Arg31Trp) variant of GNA11 (P29992)
R31W (p.Arg31Trp) in GNA11 (P29992) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
R31W (p.Arg31Trp) variant details
- p.Arg31Trp
- TOPMed rs1599293133
- Missense
- Variant Prioritization Score for Impact Estimate 0.641
- REVEL 0.75
- CADD 27.60
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available