A8A (p.Ala8Ala) variant of GNA11 (P29992)
A8A (p.Ala8Ala) in GNA11 (P29992) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
A8A (p.Ala8Ala) variant details
- p.Ala8Ala
- gnomAD 19-3094675-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.668
- AlphaMissense 0.51
- MetaLR 0.81
- MetaSVM 0.81
- CADD 15.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available