K31R (p.Lys31Arg) variant of GCK (Hexokinase-4)
K31R (p.Lys31Arg) in GCK (Hexokinase-4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
K31R (p.Lys31Arg) variant details
- p.Lys31Arg
- TOPMed rs2096283274
- gnomAD rs2096283274
- Missense
- Variant Prioritization Score for Impact Estimate 0.522
- REVEL 0.48
- CADD 21.60
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available