K31N (p.Lys31Asn) variant of GCK (Hexokinase-4)
K31N (p.Lys31Asn) in GCK (Hexokinase-4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
K31N (p.Lys31Asn) variant details
- p.Lys31Asn
- gnomAD rs1194717950
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.47
- CADD 16.90
- PolyPhen-2 0.18
- SIFT 0.49
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available