E96K (p.Glu96Lys) variant of GCK (Hexokinase-4)
E96K (p.Glu96Lys) in GCK (Hexokinase-4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
E96K (p.Glu96Lys) variant details
- p.Glu96Lys
- cosmic curated COSV61756
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.38
- CADD 18.30
- PolyPhen-2 0.10
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available