A84S (p.Ala84Ser) variant of GATA5 (Transcription factor GATA-5)
A84S (p.Ala84Ser) in GATA5 (Transcription factor GATA-5) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A84S (p.Ala84Ser) variant details
- p.Ala84Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.22
- MetaLR 0.67
- MetaSVM 0.03
- CADD 7.15
- PolyPhen-2 0.02
- SIFT 0.74
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available