S25I (p.Ser25Ile) variant of GABRA1 (P14867)
S25I (p.Ser25Ile) in GABRA1 (P14867) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
S25I (p.Ser25Ile) variant details
- p.Ser25Ile
- TOPMed rs1363320617
- gnomAD rs1363320617
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.39
- CADD 34.00
- PolyPhen-2 0.28
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available